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Why are male mice afraid of bananas?


Why are male mice afraid of bananas?
Olfactory publicity to late-pregnant and lactating mice produces analgesia in male however not feminine mice within the radiant warmth paw-withdrawal check. (A and B) Latency to hind paw-withdrawal (s) from radiant warmth of male (A) and feminine (B) mice earlier than (Pre) and through (Put up) publicity to stimulus mice of assorted reproductive circumstances: naïve male, naïve feminine (NF), early pregnant (EP), late pregnant (LP), lactating (Lact.) [with pups present (+ pups), without pups present (− pups), and with pups removed 24 hours before (− pups 24 hours)], and after weaning. (C and D) Change (Δ) in hind paw-withdrawal latency (Put up-Pre) in all stimulus circumstances proven in graphs (A) and (B) in male (C) and feminine (D) mice. Optimistic values (inexperienced) symbolize analgesia; unfavourable values (pink) symbolize hyperalgesia. In all graphs, particular person information are proven (n = 10 to 12 mice per intercourse per situation); black bars symbolize means ± SEM. *P Science Advances (2022). DOI: 10.1126/sciadv.abi9366

Researchers from McGill College have recognized a type of chemical signaling in mice to defend their offspring. The researchers discovered that proximity to pregnant and lactating feminine mice elevated stress hormones in males and even decreased their sensitivity to ache.

„The findings have vital implications for bettering the reliability and reproducibility of experiments involving mice. That is yet one more instance of a beforehand unknown issue within the lab surroundings that may have an effect on the outcomes of scientific research,“ says Jeffrey Mogil, a Professor within the Division of Psychology at McGill College and E. P. Taylor Chair in Ache Research.

In accordance with co-author Sarah Rosen, „what is probably going occurring is that feminine mice are signaling to males who is perhaps contemplating attacking their infants that they may defend them vigorously. It is the specter of the doable upcoming struggle that causes the stress.“

„Mice have richer communication with each other than we predict; it is simply that a variety of it is by odor,“ says Mogil. The researchers began in search of the olfactory chemical accountable. A number of odorants had been recognized, however one, n-pentyl acetate, which is launched within the urine of pregnant and lactating , was particularly efficient at producing stress in .

„Curiously, n-pentyl acetate can also be answerable for the distinctive odor of bananas. After a fast journey to the grocery store for some banana oil, we had been in a position to verify that the odor of banana extract burdened the male mice simply as a lot because the pregnant females,“ says co-author Lucas Lima.

The discovering represents a breakthrough within the science of mammalian social signaling. „There are a selection of examples of male-to-female olfactory signaling in rodents, however far fewer examples of female-to-male signaling, particularly exterior of the realm of sexual conduct,“ says Mogil.

„Olfactory publicity to late-pregnant and lactating mice causes stress-induced analgesia in male mice“ by Sarah Rosen et al. was revealed in Science Advances.


Neuroscientists says it’s time to begin utilizing extra feminine mice for testing


Extra data:
Sarah F. Rosen et al, Olfactory publicity to late-pregnant and lactating mice causes stress-induced analgesia in male mice, Science Advances (2022). DOI: 10.1126/sciadv.abi9366

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McGill College


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Why are male mice afraid of bananas? (2022, Might 24)
retrieved 24 Might 2022
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